A Leap above Friedewald Formula for Calculation of Low-Density Lipoprotein-Cholesterol
نویسندگان
چکیده
منابع مشابه
Comparison of friedewald formula and modified friedewald formula with direct homogeneous assay for low density lipoprotein cholesterol estimation.
OBJECTIVE To compare the Friedewald and modified Friedewald formulae with direct homogeneous assay for serum lowdensity lipoprotein cholesterol (LDL-C) levels estimation. STUDY DESIGN Cross-sectional study. PLACE AND DURATION OF STUDY Armed Forces Institute of Pathology, Rawalpindi, from June to December 2011. METHODOLOGY Healthy subjects of either gender, from Rawalpindi, aged 18-75 year...
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The calculation of serum low-density lipoprotein cholesterol (LDL-C) by the Friedewald formula does not account for the cholesterol associated with lipoprotein(a) [Lp(a)]. To quantify the contribution of Lp(a) cholesterol to total serum cholesterol, we measured concentrations of serum Lp(a) by an ELISA and concentrations of other serum lipids and lipoproteins by standard assays in 23 normolipem...
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The accuracy of the Friedewald formula in estimating low-density lipoprotein (LDL) cholesterol was investigated in 47 alcoholic patients with liver disease (21 minimal-change, 26 cirrhotic) by comparing the results with those obtained by sequential preparative ultracentrifugation. In 14% of subjects with minimal-change disease, the error in the estimated LDL cholesterol was 50% +/- 9% (mean +/-...
متن کاملIs Friedewald formula a good estimation for low density lipoprotein level in Iranian population?
OBJECTIVE Serum low density lipoprotein (LDL) level is an important biomarker for coronary artery disease (CAD). As direct LDL measurement is expensive and not cost effective, especially in a large population, it is estimated by Friedewald formula. Therefore, we decided to compare the direct LDL measurement method with LDL measured by Friedewald formula in a large general population for the fir...
متن کاملLipoprotein(a) further invalidates Friedewald formula.
92% had THCA concentrations 30 zgfL. Of the 97 specimens that screened negative at 100 pgfL, 80% had quantitative values for THCA of 30 p gfL. This suggests that reducing the screening cutoff to 50 pgIL will not result in laboratories being flooded with large numbers of specimens for which the THCA concentrations are within 20% of the 15 ig/L confirmation cutoff. The THCA-positive detection rat...
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ژورنال
عنوان ژورنال: Journal of Laboratory Physicians
سال: 2015
ISSN: 0974-2727,0974-7826
DOI: 10.4103/0974-2727.154780